USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: PRPS2_HUMAN USC-OGP 2-DE database:  PRPS2_HUMAN PRPS2_HUMAN General information about the entry View entry in simple text format Entry name PRPS2_HUMAN Primary accession number P11908 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ribose-phosphate pyrophosphokinase 2; EC=2.7.6.1; AltName: Full=PPRibP; AltName: Full=Phosphoribosyl pyrophosphate synthase II; Short=PRS-II;. Gene name Name=PRPS2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1234: pI=6.98; Mw=33419 Cross-references UniProtKB/Swiss-Prot P11908; PRPS2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PRPS2_HUMAN Primary accession number P11908 Secondary accession number(s) Q0VDH9 Q0VDI0 Q15245 Q2TAK7 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 184) Name and origin of the protein Description RecName: Full=Ribose-phosphate pyrophosphokinase 2; EC=2.7.6.1; AltName: Full=PPRibP; AltName: Full=Phosphoribosyl pyrophosphate synthase II; Short=PRS-II; Gene name Name=PRPS2 Encoded on Name=PRPS2 Keywords Alternative splicing; ATP-binding; Complete proteome; Direct protein sequencing; Kinase; Magnesium; Metal-binding; Nucleotide biosynthesis; Nucleotide-binding; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Y00971; CAA68785.1; -; mRNA EMBL BC030019; AAH30019.2; ALT_INIT; mRNA EMBL BC040483; AAH40483.3; -; mRNA EMBL BC110875; AAI10876.2; -; mRNA EMBL BC119662; AAI19663.1; -; mRNA EMBL BC119663; AAI19664.1; -; mRNA EMBL D28134; BAA05676.1; -; Genomic_DNA CCDS CCDS14150.1; -. [P11908-1]; . CCDS CCDS43918.1; -. [P11908-2]; . PIR S02778; KIHUR2; . RefSeq NP_001034180.1; NM_001039091.2. [P11908-2]; . RefSeq NP_002756.1; NM_002765.4. [P11908-1]; . UniGene Hs.654581; -; . ProteinModelPortal P11908; -; . SMR P11908; -; . BioGrid 111617; 21; . IntAct P11908; 10; . MINT MINT-5000929; -; . STRING 9606.ENSP00000381504; -; . iPTMnet P11908; -; . PhosphoSitePlus P11908; -; . SwissPalm P11908; -; . BioMuta PRPS2; -; . DMDM 125583; -; . REPRODUCTION-2DPAGE IPI00219617; -; . REPRODUCTION-2DPAGE P11908; -; . EPD P11908; -; . MaxQB P11908; -; . PaxDb P11908; -; . PeptideAtlas P11908; -; . PRIDE P11908; -; . DNASU 5634; -; . Ensembl ENST00000380668; ENSP00000370043; ENSG00000101911. [P11908-1]; . Ensembl ENST00000398491; ENSP00000381504; ENSG00000101911. [P11908-2]; . GeneID 5634; -; . KEGG hsa:5634; -; . UCSC uc004cva.4; human. [P11908-1]; . CTD 5634; -; . DisGeNET 5634; -; . GeneCards PRPS2; -; . HGNC HGNC:9465; PRPS2; . HPA CAB070417; -; . MIM 311860; gene; . neXtProt NX_P11908; -; . OpenTargets ENSG00000101911; -; . PharmGKB PA33820; -; . eggNOG KOG1448; Eukaryota; . eggNOG COG0462; LUCA; . GeneTree ENSGT00550000074583; -; . HOGENOM HOG000210451; -; . HOVERGEN HBG001520; -; . InParanoid P11908; -; . KO K00948; -; . OMA ENITEWK; -; . OrthoDB EOG091G0ZG8; -; . PhylomeDB P11908; -; . TreeFam TF106366; -; . BioCyc MetaCyc:HS02317-MONOMER; -; . Reactome R-HSA-73843; 5-Phosphoribose 1-diphosphate biosynthesis; . UniPathway UPA00087; UER00172; . ChiTaRS PRPS2; human; . GenomeRNAi 5634; -; . PRO PR:P11908; -; . Proteomes UP000005640; Chromosome X; . Bgee ENSG00000101911; -; . CleanEx HS_PRPS2; -; . ExpressionAtlas P11908; baseline and differential; . Genevisible P11908; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0043234; C:protein complex; IEA:Ensembl; . GO GO:0002189; C:ribose phosphate diphosphokinase complex; IEA:Ensembl; . GO GO:0043531; F:ADP binding; IEA:Ensembl; . GO GO:0016208; F:AMP binding; IEA:Ensembl; . GO GO:0005524; F:ATP binding; ISS:UniProtKB; . GO GO:0030246; F:carbohydrate binding; IEA:Ensembl; . GO GO:0019003; F:GDP binding; IEA:Ensembl; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0016301; F:kinase activity; IEA:UniProtKB-KW; . GO GO:0000287; F:magnesium ion binding; IEA:Ensembl; . GO GO:0042803; F:protein homodimerization activity; ISS:UniProtKB; . GO GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB; . GO GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IEA:UniProtKB-UniPathway; . GO GO:0006167; P:AMP biosynthetic process; IEA:Ensembl; . GO GO:0031100; P:animal organ regeneration; IEA:Ensembl; . GO GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc; . CDD cd06223; PRTases_typeI; 1; . Gene3D 3.40.50.2020; -; 2; . HAMAP MF_00583_B; RibP_PPkinase_B; 1; . InterPro IPR000842; PRib_PP_synth_CS; . InterPro IPR029099; Pribosyltran_N; . InterPro IPR000836; PRibTrfase_dom; . InterPro IPR029057; PRTase-like; . InterPro IPR005946; Rib-P_diPkinase; . Pfam PF14572; Pribosyl_synth; 1; . Pfam PF13793; Pribosyltran_N; 1; . SUPFAM SSF53271; SSF53271; 1; . TIGRFAMs TIGR01251; ribP_PPkin; 1; . PROSITE PS00114; PRPP_SYNTHASE; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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